1H7W

Dihydropyrimidine dehydrogenase (DPD) from pig

Summary for 1H7W

Entry DOI	10.2210/pdb1h7w/pdb
Related	1H7X
Descriptor	DIHYDROPYRIMIDINE DEHYDROGENASE, IRON/SULFUR CLUSTER, FLAVIN MONONUCLEOTIDE, ... (5 entities in total)
Functional Keywords	electron transfer, flavin, iron-sulfur clusters, pyrimidine catabolism, oxidoreductase
Biological source	SUS SCROFA (WILD BOAR)
Total number of polymer chains	4
Total formula weight	457007.19
Authors	Dobritzsch, D.,Schneider, G.,Schnackerz, K.D.,Lindqvist, Y. (deposition date: 2001-01-19, release date: 2001-02-23, Last modification date: 2019-01-23)
Primary citation	Dobritzsch, D.,Schneider, G.,Schnackerz, K.D.,Lindqvist, Y. Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J., 20:650-660, 2001 Cited by PubMed: 11179210 DOI: 10.1093/emboj/20.4.650 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation