1GYQ
CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD
Summary for 1GYQ
Entry DOI | 10.2210/pdb1gyq/pdb |
Descriptor | PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total) |
Functional Keywords | oxidoreductase (aldehyde(d)-nad+(a)), oxidoreductase |
Biological source | Leishmania mexicana |
Cellular location | Glycosome: Q27890 |
Total number of polymer chains | 4 |
Total formula weight | 157786.71 |
Authors | Suresh, S.,Hol, W. (deposition date: 1999-03-05, release date: 1999-03-16, Last modification date: 2023-08-09) |
Primary citation | Aronov, A.M.,Suresh, S.,Buckner, F.S.,Van Voorhis, W.C.,Verlinde, C.L.,Opperdoes, F.R.,Hol, W.G.,Gelb, M.H. Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase. Proc.Natl.Acad.Sci.USA, 96:4273-4278, 1999 Cited by PubMed: 10200252DOI: 10.1073/pnas.96.8.4273 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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