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1GYQ

CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD

Summary for 1GYQ
Entry DOI10.2210/pdb1gyq/pdb
DescriptorPROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total)
Functional Keywordsoxidoreductase (aldehyde(d)-nad+(a)), oxidoreductase
Biological sourceLeishmania mexicana
Cellular locationGlycosome: Q27890
Total number of polymer chains4
Total formula weight157786.71
Authors
Suresh, S.,Hol, W. (deposition date: 1999-03-05, release date: 1999-03-16, Last modification date: 2023-08-09)
Primary citationAronov, A.M.,Suresh, S.,Buckner, F.S.,Van Voorhis, W.C.,Verlinde, C.L.,Opperdoes, F.R.,Hol, W.G.,Gelb, M.H.
Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.
Proc.Natl.Acad.Sci.USA, 96:4273-4278, 1999
Cited by
PubMed: 10200252
DOI: 10.1073/pnas.96.8.4273
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation

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