1GXD

proMMP-2/TIMP-2 complex

Summary for 1GXD

Entry DOI	10.2210/pdb1gxd/pdb
Related	1BR9 1CK7 1CXW 1EAK 1GEN 1J7M 1KS0 1RTG 2TMP
Descriptor	72 KDA TYPE IV COLLAGENASE, METALLOPROTEINASE INHIBITOR 2, SULFATE ION, ... (5 entities in total)
Functional Keywords	hydrolase, metalloprotease, zymogen, collagen degradation, extracellular matrix, gelatinase a, matrix metalloproteinase 2, proteinase inhibitor
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	4
Total formula weight	186090.81
Authors	Morgunova, E.,Tuuttila, A.,Bergmann, U.,Tryggvason, K. (deposition date: 2002-04-02, release date: 2002-07-09, Last modification date: 2023-12-13)
Primary citation	Morgunova, E.,Tuuttila, A.,Bergmann, U.,Tryggvason, K. Structural Insight Into the Complex Formation of Latent Matrix Metalloproteinase 2 with Tissue Inhibitor of Metalloproteinase 2 Proc.Natl.Acad.Sci.USA, 99:7414-, 2002 Cited by PubMed: 12032297 DOI: 10.1073/PNAS.102185399 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation