1GUA

HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131

Summary for 1GUA

Entry DOI	10.2210/pdb1gua/pdb
Descriptor	RAP1A, C-RAF1, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	oncogene protein/kinase/effector protein gtp-binding-protein, complex (gtp-binding-atp-binding), complex (gtp-binding-atp-binding) complex, complex (gtp-binding/atp-binding)
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Lipid-anchor: P62834 Cytoplasm (By similarity): P04049
Total number of polymer chains	2
Total formula weight	28831.89
Authors	Nassar, N.,Wittinghofer, A. (deposition date: 1996-06-18, release date: 1997-01-11, Last modification date: 2024-02-07)
Primary citation	Nassar, N.,Horn, G.,Herrmann, C.,Block, C.,Janknecht, R.,Wittinghofer, A. Ras/Rap effector specificity determined by charge reversal. Nat.Struct.Biol., 3:723-729, 1996 Cited by PubMed: 8756332 DOI: 10.1038/nsb0896-723 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation