1GH6

RETINOBLASTOMA POCKET COMPLEXED WITH SV40 LARGE T ANTIGEN

Summary for 1GH6

• Entry DOI: 10.2210/pdb1gh6/pdb
• Descriptor: Large T antigen, Retinoblastoma-associated protein (2 entities in total)
• Functional Keywords: tumor suppressor, oncoprotein, antitumor protein
• Biological source: Simian virus 40 (SV40); More
• Cellular location: Host nucleus : P03070; Nucleus : P06400
• Total number of polymer chains: 2
• Total formula weight: 52463.49

Authors

Kim, H.Y.,Cho, Y. (deposition date: 2000-11-15, release date: 2001-11-15, Last modification date: 2023-08-09)

• Primary citation: Kim, H.Y.,Ahn, B.Y.,Cho, Y.; Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen.; EMBO J., 20:295-304, 2001; PubMed: 11226179; DOI: 10.1093/emboj/20.1.295

Experimental method

X-RAY DIFFRACTION (3.2 Å)