1GCZ

MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) COMPLEXED WITH INHIBITOR.

Summary for 1GCZ

• Entry DOI: 10.2210/pdb1gcz/pdb
• Related: 1GD0
• Descriptor: MACROPHAGE MIGRATION INHIBITORY FACTOR, SULFATE ION, CITRIC ACID, ... (5 entities in total)
• Functional Keywords: protein-inhibitor complex, mif, macrophage migration inhibitory factor, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P14174
• Total number of polymer chains: 3
• Total formula weight: 42518.24

Authors

Katayama, N.,Kurihara, H. (deposition date: 2000-08-24, release date: 2001-02-21, Last modification date: 2024-03-20)

• Primary citation: Orita, M.,Yamamoto, S.,Katayama, N.,Aoki, M.,Takayama, K.,Yamagiwa, Y.,Seki, N.,Suzuki, H.,Kurihara, H.,Sakashita, H.,Takeuchi, M.,Fujita, S.,Yamada, T.,Tanaka, A.; Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.; J.Med.Chem., 44:540-547, 2001; PubMed: 11170644; DOI: 10.1021/jm000386o

Experimental method

X-RAY DIFFRACTION (1.9 Å)