1GC1

HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY

1GC1 の概要

• エントリーDOI: 10.2210/pdb1gc1/pdb
• 分子名称: ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B, ... (7 entities in total)
• 機能のキーワード: complex (hiv envelope protein-cd4-fab), hiv-1 exterior envelope gp120, t-cell surface glycoprotein cd4, antigen-binding fragment of human immunoglobulin 17b, glycosylated protein, viral protein-receptor-immune system complex, viral protein/receptor/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 106802.56

構造登録者

Kwong, P.D.,Wyatt, R.,Robinson, J.,Sweet, R.W.,Sodroski, J.,Hendrickson, W.A. (登録日: 1998-06-15, 公開日: 1998-07-08, 最終更新日: 2023-08-09)

• 主引用文献: Kwong, P.D.,Wyatt, R.,Robinson, J.,Sweet, R.W.,Sodroski, J.,Hendrickson, W.A.; Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.; Nature, 393:648-659, 1998; PubMed: 9641677; DOI: 10.1038/31405

実験手法

X-RAY DIFFRACTION (2.5 Å)