1GA9

CRYSTAL STRUCTURE OF AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH NON-BETA-LACTAMASE INHIBITOR (2, 3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PHENYLBORONIC ACID)

Summary for 1GA9

Entry DOI	10.2210/pdb1ga9/pdb
Related	1C3B 2BLS 3BLS
Descriptor	BETA-LACTAMASE, PHOSPHATE ION, 3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PHENYLBORONIC ACID, ... (5 entities in total)
Functional Keywords	cephalosporinase, beta-lactamase, serine hydrolase, hydrolase
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	80251.47
Authors	Tondi, D.,Powers, R.A.,Caselli, E.,Negri, M.C.,Blazquez, J.,Costi, M.P.,Shoichet, B.K. (deposition date: 2000-11-29, release date: 2001-07-25, Last modification date: 2023-08-09)
Primary citation	Tondi, D.,Powers, R.A.,Caselli, E.,Negri, M.C.,Blazquez, J.,Costi, M.P.,Shoichet, B.K. Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase. Chem.Biol., 8:593-611, 2001 Cited by PubMed: 11410378 DOI: 10.1016/S1074-5521(01)00034-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation