1G6I

Crystal structure of the yeast alpha-1,2-mannosidase with bound 1-deoxymannojirimycin at 1.59 A resolution

Summary for 1G6I

• Entry DOI: 10.2210/pdb1g6i/pdb
• Descriptor: CLASS I ALPHA-1,2-MANNOSIDASE, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: alpha-alpha7 barrel, hydrolase
• Biological source: Saccharomyces cerevisiae (yeast)
• Total number of polymer chains: 1
• Total formula weight: 65202.87

Authors

Herscovics, A.,Lipari, F.,Sleno, B.,Romera, P.A.,Vallee, F.,Yip, P.,Howell, P.A. (deposition date: 2000-11-06, release date: 2003-06-24, Last modification date: 2024-04-03)

• Primary citation: Herscovics, A.,Lipari, F.,Sleno, B.,Romera, P.A.,Vallee, F.,Yip, P.,Howell, P.A.; Structure and function of Class I a1,2-mannosidases involved in glycoprotein biosynthesis.; CARBOHYDRATE BIOENGINEERING. INTERDISCIPLINARY APPROACHES., :28-33, 2002

Experimental method

X-RAY DIFFRACTION (1.59 Å)