1G3X

INTERCALATION OF AN 9ACRIDINE-PEPTIDE DRUG IN A DNA DODECAMER

Summary for 1G3X

• Entry DOI: 10.2210/pdb1g3x/pdb
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', N(ALPHA)-(9-ACRIDINOYL)-TETRAARGININE-AMIDE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: dna, drug-peptide adduct, intercalation, mg+2 ions
• Total number of polymer chains: 13
• Total formula weight: 44966.84

Authors

Malinina, L.,Soler-Lopez, M.,Aymami, J.,Subirana, J.A. (deposition date: 2000-10-25, release date: 2002-08-16, Last modification date: 2011-07-13)

• Primary citation: Malinina, L.,Soler-Lopez, M.,Aymami, J.,Subirana, J.A.; Intercalation of an acridine-peptide drug in an AA/TT base step in the crystal structure of [d(CGCGAATTCGCG)](2) with six duplexes and seven Mg(2+) ions in the asymmetric unit.; Biochemistry, 41:9341-9348, 2002; PubMed: 12135355; DOI: 10.1021/bi020135c

Experimental method

X-RAY DIFFRACTION (2.7 Å)