1G30

THROMBIN INHIBITOR COMPLEX

1G30 の概要

• エントリーDOI: 10.2210/pdb1g30/pdb
• 分子名称: PROTHROMBIN, HIRUDIN IIB, [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER, ... (5 entities in total)
• 機能のキーワード: blood coagulation, factor xa, inhibitor complexes, serine proteinase, blood coagulation cascade, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35893.88

構造登録者

Nar, H. (登録日: 2000-10-23, 公開日: 2001-10-23, 最終更新日: 2018-10-03)

• 主引用文献: Nar, H.,Bauer, M.,Schmid, A.,Stassen, J.M.,Wienen, W.,Priepke, H.W.,Kauffmann, I.K.,Ries, U.J.,Hauel, N.H.; Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.; Structure, 9:29-38, 2001; PubMed: 11342132; DOI: 10.1016/S0969-2126(00)00551-7

実験手法

X-RAY DIFFRACTION (2 Å)