1G30

THROMBIN INHIBITOR COMPLEX

Summary for 1G30

• Entry DOI: 10.2210/pdb1g30/pdb
• Descriptor: PROTHROMBIN, HIRUDIN IIB, [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER, ... (5 entities in total)
• Functional Keywords: blood coagulation, factor xa, inhibitor complexes, serine proteinase, blood coagulation cascade, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 35893.88

Authors

Nar, H. (deposition date: 2000-10-23, release date: 2001-10-23, Last modification date: 2018-10-03)

• Primary citation: Nar, H.,Bauer, M.,Schmid, A.,Stassen, J.M.,Wienen, W.,Priepke, H.W.,Kauffmann, I.K.,Ries, U.J.,Hauel, N.H.; Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.; Structure, 9:29-38, 2001; PubMed: 11342132; DOI: 10.1016/S0969-2126(00)00551-7

Experimental method

X-RAY DIFFRACTION (2 Å)