1G1O

CRYSTAL STRUCTURE OF THE HIGHLY AMYLOIDOGENIC TRANSTHYRETIN MUTANT TTR G53S/E54D/L55S

Summary for 1G1O

Entry DOI	10.2210/pdb1g1o/pdb
Descriptor	TRANSTHYRETIN (2 entities in total)
Functional Keywords	greek key, beta barrel, beta-slip, transport protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	4
Total formula weight	55069.12
Authors	Eneqvist, T.,Andersson, K.,Olofsson, A.,Lundgren, E.,Sauer-Eriksson, A.E. (deposition date: 2000-10-13, release date: 2001-10-17, Last modification date: 2024-02-07)
Primary citation	Eneqvist, T.,Andersson, K.,Olofsson, A.,Lundgren, E.,Sauer-Eriksson, A.E. The beta-slip: a novel concept in transthyretin amyloidosis. Mol.Cell, 6:1207-1218, 2000 Cited by PubMed: 11106758 DOI: 10.1016/S1097-2765(00)00117-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation