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1FYX

CRYSTAL STRUCTURE OF P681H MUTANT OF TIR DOMAIN OF HUMAN TLR2

Summary for 1FYX
Entry DOI10.2210/pdb1fyx/pdb
Related1FYV 1FYW
DescriptorTOLL-LIKE RECEPTOR 2 (1 entity in total)
Functional Keywordsbeta-alpha-beta fold, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationMembrane ; Single-pass type I membrane protein : O60603
Total number of polymer chains1
Total formula weight18355.54
Authors
Xu, Y.,Tao, X.,Shen, B.,Horng, T.,Medzhitov, R.,Manley, J.L.,Tong, L. (deposition date: 2000-10-03, release date: 2000-11-22, Last modification date: 2021-11-03)
Primary citationXu, Y.,Tao, X.,Shen, B.,Horng, T.,Medzhitov, R.,Manley, J.L.,Tong, L.
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408:111-115, 2000
Cited by
PubMed: 11081518
DOI: 10.1038/35047056
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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