1FVC

X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING

Summary for 1FVC

Entry DOI	10.2210/pdb1fvc/pdb
Descriptor	IGG1-KAPPA 4D5 FV (LIGHT CHAIN), IGG1-KAPPA 4D5 FV (HEAVY CHAIN) (3 entities in total)
Functional Keywords	immunoglobulin
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	50281.89
Authors	Eigenbrot, C.,Randal, M.,Kossiakoff, A.A.,Presta, L. (deposition date: 1992-10-20, release date: 1993-10-31, Last modification date: 2017-11-29)
Primary citation	Eigenbrot, C.,Randal, M.,Presta, L.,Carter, P.,Kossiakoff, A.A. X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. J.Mol.Biol., 229:969-995, 1993 Cited by PubMed: 8095303 DOI: 10.1006/jmbi.1993.1099 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation