1FV1

STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES

1FV1 の概要

• エントリーDOI: 10.2210/pdb1fv1/pdb
• 分子名称: MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, MYELIN BASIC PROTEIN, ... (6 entities in total)
• 機能のキーワード: mhc class ii dr2a, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: P01903 Q30154; Myelin membrane; Peripheral membrane protein; Cytoplasmic side: P02686
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 91662.43

構造登録者

Li, H.,Mariuzza, A.R.,Li, Y.,Martin, R. (登録日: 2000-09-18, 公開日: 2000-09-27, 最終更新日: 2011-07-13)

• 主引用文献: Li, Y.,Li, H.,Martin, R.,Mariuzza, R.A.; Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.; J.Mol.Biol., 304:177-188, 2000; PubMed: 11080454; DOI: 10.1006/jmbi.2000.4198

実験手法

X-RAY DIFFRACTION (1.9 Å)