1FTL

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH THE ANTAGONIST DNQX AT 1.8 A RESOLUTION

Summary for 1FTL

• Entry DOI: 10.2210/pdb1ftl/pdb
• Related: 1FTJ 1FTK 1FTM 1FTO 1FW0 1GR2
• Descriptor: GLUTAMATE RECEPTOR SUBUNIT 2, 6,7-DINITROQUINOXALINE-2,3-DIONE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: glutamate receptor, s1s2, ligand binding core, antagonist, dnqx, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 2
• Total formula weight: 59039.68

Authors

Armstrong, N.,Gouaux, E. (deposition date: 2000-09-12, release date: 2000-11-01, Last modification date: 2017-08-02)

• Primary citation: Armstrong, N.,Gouaux, E.; Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.; Neuron, 28:165-181, 2000; PubMed: 11086992; DOI: 10.1016/S0896-6273(00)00094-5

Experimental method

X-RAY DIFFRACTION (1.8 Å)