1FTH

CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE ACYL CARRIER PROTEIN SYNTHASE (3'5'-ADP COMPLEX)

Summary for 1FTH

Entry DOI	10.2210/pdb1fth/pdb
Descriptor	ACYL CARRIER PROTEIN SYNTHASE, ADENOSINE-3'-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	bacterial fatty acid biosynthesis, acyl carrier synthase, coenzyme a, structure-based drug design, transferase
Biological source	Streptococcus pneumoniae
Cellular location	Cytoplasm (By similarity): P0A2W6
Total number of polymer chains	3
Total formula weight	41889.92
Authors	Chirgadze, N.,Briggs, S.,McAllister, K.,Fischl, A.,Zhao, G. (deposition date: 2000-09-12, release date: 2001-09-12, Last modification date: 2023-08-09)
Primary citation	Chirgadze, N.Y.,Briggs, S.L.,McAllister, K.A.,Fischl, A.S.,Zhao, G. Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis. EMBO J., 19:5281-5287, 2000 Cited by PubMed: 11032795 DOI: 10.1093/emboj/19.20.5281 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation