1FTD

5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'-SYMMETRIC BIS-BENZIMIDAZOLE COMPLEX

1FTD の概要

• エントリーDOI: 10.2210/pdb1ftd/pdb
• 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, [3-(4-{2'-[4-(3-DIMETHYLAMINO-PROPOXY)-PHENYL]-3H,3'H-[5,5']BIBENZOIMIDAZOLYL-2-YL}-PHENOXY)-PROPYL]-DIMETHYL-AMINE, ... (4 entities in total)
• 機能のキーワード: minor groove binding, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7939.83

構造登録者

Mann, J.,Baron, A.,Opoku-Boahen, Y.,Johansson, E.,Parkinson, G.,Kelland, L.R.,Neidle, S. (登録日: 2000-09-12, 公開日: 2001-02-26, 最終更新日: 2024-02-07)

• 主引用文献: Mann, J.,Baron, A.,Opoku-Boahen, Y.,Johansson, E.,Parkinson, G.,Kelland, L.R.,Neidle, S.; A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.; J.Med.Chem., 44:138-144, 2001; PubMed: 11170623; DOI: 10.1021/jm000297b

実験手法

X-RAY DIFFRACTION (2 Å)