1FSG

TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS

Summary for 1FSG

Entry DOI	10.2210/pdb1fsg/pdb
Related	1BZY 1DBR 1HMP 1QK3 1QK4 1QK5 1TC2
Descriptor	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ... (5 entities in total)
Functional Keywords	glycosyltransferase, purine salvage, transferase
Biological source	Toxoplasma gondii
Cellular location	Cytoplasm: Q26997
Total number of polymer chains	2
Total formula weight	54588.64
Authors	Heroux, A.,White, E.L.,Ross, L.J.,Kuzin, A.P.,Borhani, D.W. (deposition date: 2000-09-08, release date: 2000-12-06, Last modification date: 2024-04-03)
Primary citation	Heroux, A.,White, E.L.,Ross, L.J.,Kuzin, A.P.,Borhani, D.W. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis. Structure Fold.Des., 8:1309-1318, 2000 Cited by PubMed: 11188695 DOI: 10.1016/S0969-2126(00)00546-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.05 Å)

Structure validation