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1FH0

CRYSTAL STRUCTURE OF HUMAN CATHEPSIN V COMPLEXED WITH AN IRREVERSIBLE VINYL SULFONE INHIBITOR

Summary for 1FH0
Entry DOI10.2210/pdb1fh0/pdb
Related PRD IDPRD_000325
DescriptorCATHEPSIN V, Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide, SULFATE ION, ... (4 entities in total)
Functional Keywordscathepsin, papain, protease, cancer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationLysosome : O60911
Total number of polymer chains2
Total formula weight49331.48
Authors
Somoza, J.R. (deposition date: 2000-07-30, release date: 2001-07-30, Last modification date: 2024-03-13)
Primary citationSomoza, J.R.,Zhan, H.,Bowman, K.K.,Yu, L.,Mortara, K.D.,Palmer, J.T.,Clark, J.M.,McGrath, M.E.
Crystal structure of human cathepsin V.
Biochemistry, 39:12543-12551, 2000
Cited by
PubMed: 11027133
DOI: 10.1021/bi000951p
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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