1FDT
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRADIOL AND NADP+
Summary for 1FDT
Entry DOI | 10.2210/pdb1fdt/pdb |
Descriptor | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE, SULFATE ION, ESTRADIOL, ... (5 entities in total) |
Functional Keywords | dehydrogenase, 17-beta-hydroxysteroid |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14061 |
Total number of polymer chains | 1 |
Total formula weight | 36085.79 |
Authors | Housset, D.,Breton, R.,Mazza, C.,Fontecilla-Camps, J.-C. (deposition date: 1996-06-28, release date: 1997-02-12, Last modification date: 2011-07-13) |
Primary citation | Breton, R.,Housset, D.,Mazza, C.,Fontecilla-Camps, J.C. The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors. Structure, 4:905-915, 1996 Cited by PubMed: 8805577DOI: 10.1016/S0969-2126(96)00098-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report