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1FDT

HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRADIOL AND NADP+

Summary for 1FDT
Entry DOI10.2210/pdb1fdt/pdb
Descriptor17-BETA-HYDROXYSTEROID-DEHYDROGENASE, SULFATE ION, ESTRADIOL, ... (5 entities in total)
Functional Keywordsdehydrogenase, 17-beta-hydroxysteroid
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P14061
Total number of polymer chains1
Total formula weight36085.79
Authors
Housset, D.,Breton, R.,Mazza, C.,Fontecilla-Camps, J.-C. (deposition date: 1996-06-28, release date: 1997-02-12, Last modification date: 2011-07-13)
Primary citationBreton, R.,Housset, D.,Mazza, C.,Fontecilla-Camps, J.C.
The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors.
Structure, 4:905-915, 1996
Cited by
PubMed: 8805577
DOI: 10.1016/S0969-2126(96)00098-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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