1FD5

BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (BISACRIDINE COMPLEX)

1FD5 の概要

• エントリーDOI: 10.2210/pdb1fd5/pdb
• 分子名称: DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), COBALT (II) ION, MACROCYCLIC-BIS-9-AMINO-ACRIDINE, ... (5 entities in total)
• 機能のキーワード: high resolution crystal structure, intercalation platform, mad, anticancer drug, drug-dna complex, metal ions, tertiary base pairs, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 4579.74

構造登録者

Yang, X.-L.,Robinson, H.,Gao, Y.-G.,Wang, A.H.-J. (登録日: 2000-07-19, 公開日: 2000-08-07, 最終更新日: 2024-03-13)

• 主引用文献: Yang, X.L.,Robinson, H.,Gao, Y.G.,Wang, A.H.; Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.; Biochemistry, 39:10950-10957, 2000; PubMed: 10998231; DOI: 10.1021/bi001319z

実験手法

X-RAY DIFFRACTION (1.1 Å)