1FAV

THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE

Summary for 1FAV

Entry DOI	10.2210/pdb1fav/pdb
Descriptor	HIV-1 ENVELOPE PROTEIN CHIMERA, PROTEIN (TRANSMEMBRANE GLYCOPROTEIN) (2 entities in total)
Functional Keywords	hiv-1, gp41, inhibitor, viral protein
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Cellular location	Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03377 P03377
Total number of polymer chains	2
Total formula weight	13318.12
Authors	Zhou, G.,Ferrer, M.,Chopra, R.,Strassmaier, T.,Weissenhorn, W.,Skehel, J.J.,Oprian, D.,Schreiber, S.L.,Harrison, S.C.,Wiley, D.C. (deposition date: 2000-07-13, release date: 2000-08-23, Last modification date: 2023-11-15)
Primary citation	Zhou, G.,Ferrer, M.,Chopra, R.,Kapoor, T.M.,Strassmaier, T.,Weissenhorn, W.,Skehel, J.J.,Oprian, D.,Schreiber, S.L.,Harrison, S.C.,Wiley, D.C. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg.Med.Chem., 8:2219-2227, 2000 Cited by PubMed: 11026535 DOI: 10.1016/S0968-0896(00)00155-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation