1F8U

CRYSTAL STRUCTURE OF MUTANT E202Q OF HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH GREEN MAMBA VENOM PEPTIDE FASCICULIN-II

Summary for 1F8U

• Entry DOI: 10.2210/pdb1f8u/pdb
• Related: 1B41
• Descriptor: ACETYLCHOLINESTERASE, FASCICULIN II, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: serine esterase, human acetylcholinesterase, hydrolase, snake toxin, hydrolase/hydrolase inhibitor, hydrolase-toxin complex, hydrolase/toxin
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 71833.92

Authors

Kryger, G.,Harel, M.,Shafferman, A.,Silman, I.,Sussman, J.L. (deposition date: 2000-07-05, release date: 2001-01-17, Last modification date: 2021-11-03)

• Primary citation: Kryger, G.,Harel, M.,Giles, K.,Toker, L.,Velan, B.,Lazar, A.,Kronman, C.,Barak, D.,Ariel, N.,Shafferman, A.,Silman, I.,Sussman, J.L.; Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II.; Acta Crystallogr.,Sect.D, 56:1385-1394, 2000; PubMed: 11053835; DOI: 10.1107/S0907444900010659

Experimental method

X-RAY DIFFRACTION (2.9 Å)