1F12

L-3-HYDROXYACYL-COA DEHYDROGENASE COMPLEXED WITH 3-HYDROXYBUTYRYL-COA

Summary for 1F12

Entry DOI	10.2210/pdb1f12/pdb
Related	1F0Y 1F14 1F17 3HAD
Descriptor	L-3-HYDROXYACYL-COA DEHYDROGENASE, 3-HYDROXYBUTANOYL-COENZYME A (3 entities in total)
Functional Keywords	l-3-hydroxyacyl-coa complexed with 3-hydroxybutyryl-coa, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: Q16836
Total number of polymer chains	2
Total formula weight	68645.27
Authors	Barycki, J.J.,O'Brien, L.K.,Strauss, A.W.,Banaszak, L.J. (deposition date: 2000-05-18, release date: 2000-09-27, Last modification date: 2024-02-07)
Primary citation	Barycki, J.J.,O'Brien, L.K.,Strauss, A.W.,Banaszak, L.J. Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase. J.Biol.Chem., 275:27186-27196, 2000 Cited by PubMed: 10840044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation