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1F0S

Crystal Structure of Human Coagulation Factor XA Complexed with RPR208707

Summary for 1F0S
Entry DOI10.2210/pdb1f0s/pdb
Related1EZQ 1F0R 1F0T 1F0U
DescriptorCOAGULATION FACTOR XA, CALCIUM ION, THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE, ... (5 entities in total)
Functional Keywordsprotein-inhibitor complex, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P00742 P00742
Total number of polymer chains2
Total formula weight44228.97
Authors
Maignan, S.,Guilloteau, J.P.,Pouzieux, S.,Choi-Sledeski, Y.M.,Becker, M.R.,Klein, S.I.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V. (deposition date: 2000-05-17, release date: 2000-09-20, Last modification date: 2024-03-13)
Primary citationMaignan, S.,Guilloteau, J.P.,Pouzieux, S.,Choi-Sledeski, Y.M.,Becker, M.R.,Klein, S.I.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V.
Crystal structures of human factor Xa complexed with potent inhibitors.
J.Med.Chem., 43:3226-3232, 2000
Cited by
PubMed: 10966741
DOI: 10.1021/jm000940u
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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