1EZU

ECOTIN Y69F, D70P BOUND TO D102N TRYPSIN

Summary for 1EZU

Entry DOI	10.2210/pdb1ezu/pdb
Related	1azz 1ecy 1ecz 1ezs 1slu 1slv 1slw 1slx
Descriptor	ECOTIN, TRYPSIN II, ANIONIC, CALCIUM ION, ... (4 entities in total)
Functional Keywords	macromolecular complex, protease inhibitor, protein-protein interactions, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Escherichia coli More
Cellular location	Periplasm: P23827 Secreted, extracellular space: P00763
Total number of polymer chains	4
Total formula weight	79882.90
Authors	Gillmor, S.A.,Takeuchi, T.,Yang, S.Q.,Craik, C.S.,Fletterick, R.J. (deposition date: 2000-05-11, release date: 2000-06-23, Last modification date: 2021-11-03)
Primary citation	Gillmor, S.A.,Takeuchi, T.,Yang, S.Q.,Craik, C.S.,Fletterick, R.J. Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases. J.Mol.Biol., 299:993-1003, 2000 Cited by PubMed: 10843853 DOI: 10.1006/jmbi.2000.3812 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation