1ETZ

THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS

1ETZ の概要

• エントリーDOI: 10.2210/pdb1etz/pdb
• 関連するPDBエントリー: 1CGS 2CGR
• 分子名称: FAB NC10.14 - LIGHT CHAIN, FAB NC10.14 - HEAVY CHAIN, N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID, ... (4 entities in total)
• 機能のキーワード: anti-sweetener fab, antigen-antibody, complex, receptor mimicry, antigen recognition, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 96036.59

構造登録者

Guddat, L.W.,Shan, L.,Broomell, C.,Ramsland, P.A.,Fan, Z.,Anchin, J.M.,Linthicum, D.S.,Edmundson, A.B. (登録日: 2000-04-13, 公開日: 2000-10-18, 最終更新日: 2017-10-04)

• 主引用文献: Guddat, L.W.,Shan, L.,Broomell, C.,Ramsland, P.A.,Fan, Z.,Anchin, J.M.,Linthicum, D.S.,Edmundson, A.B.; The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.; J.Mol.Biol., 302:853-872, 2000; PubMed: 10993728; DOI: 10.1006/jmbi.2000.4083

実験手法

X-RAY DIFFRACTION (2.6 Å)