1EQU

TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+

Summary for 1EQU

Entry DOI	10.2210/pdb1equ/pdb
Descriptor	PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, EQUILIN, ... (4 entities in total)
Functional Keywords	hydroxysteroid dehydrogenase, short chain dehydrogenase, reductase, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P14061
Total number of polymer chains	2
Total formula weight	71530.82
Authors	Sawicki, M.W.,Erman, M.,Puranen, T.,Vihko, P.,Ghosh, D. (deposition date: 1998-12-02, release date: 1999-12-02, Last modification date: 2023-08-09)
Primary citation	Sawicki, M.W.,Erman, M.,Puranen, T.,Vihko, P.,Ghosh, D. Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+. Proc.Natl.Acad.Sci.USA, 96:840-845, 1999 Cited by PubMed: 9927655 DOI: 10.1073/pnas.96.3.840 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation