1EMS

CRYSTAL STRUCTURE OF THE C. ELEGANS NITFHIT PROTEIN

Summary for 1EMS

Entry DOI	10.2210/pdb1ems/pdb
Descriptor	NIT-FRAGILE HISTIDINE TRIAD FUSION PROTEIN, ETHYL MERCURY ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	worm, nitrilase, fhit, nucleotide-binding protein, cancer, diadenosine polyphosphate hydrolase, histidine triad, tumor suppressor, rosetta stone, antitumor protein
Biological source	Caenorhabditis elegans
Total number of polymer chains	2
Total formula weight	101374.28
Authors	Pace, H.C.,Hodawadekar, S.C.,Draganescu, A.,Huang, J.,Bieganowski, P.,Pekarsky, Y.,Croce, C.M.,Brenner, C. (deposition date: 2000-03-17, release date: 2000-07-20, Last modification date: 2024-02-07)
Primary citation	Pace, H.C.,Hodawadekar, S.C.,Draganescu, A.,Huang, J.,Bieganowski, P.,Pekarsky, Y.,Croce, C.M.,Brenner, C. Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers. Curr.Biol., 10:907-917, 2000 Cited by PubMed: 10959838 DOI: 10.1016/S0960-9822(00)00621-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation