1ELD

Structural analysis of the active site of porcine pancreatic elastase based on the x-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors

1ELD の概要

• エントリーDOI: 10.2210/pdb1eld/pdb
• 関連するPDBエントリー: 1ELE
• 関連するBIRD辞書のPRD_ID: PRD_000364
• 分子名称: ELASTASE, N-(trifluoroacetyl)-L-phenylalanyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (pig)
• 細胞内の位置: Secreted: P00772
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26503.55

構造登録者

Mattos, C.,Petsko, G.A.,Ringe, D. (登録日: 1994-10-24, 公開日: 1995-02-14, 最終更新日: 2012-12-12)

• 主引用文献: Mattos, C.,Giammona, D.A.,Petsko, G.A.,Ringe, D.; Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors.; Biochemistry, 34:3193-3203, 1995; PubMed: 7880814; DOI: 10.1021/bi00010a008

実験手法

X-RAY DIFFRACTION (2 Å)