1EKU

CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA

Summary for 1EKU

• Entry DOI: 10.2210/pdb1eku/pdb
• Descriptor: Interferon gamma, SULFATE ION (3 entities in total)
• Functional Keywords: cytokine, protein engineering, interferon, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P01579
• Total number of polymer chains: 2
• Total formula weight: 63019.25

Authors

Landar, A.,Curry, B.,Parker, M.H.,DiGiacomo, R.,Indelicato, S.R.,Walter, M.R. (deposition date: 2000-03-09, release date: 2000-09-01, Last modification date: 2024-02-07)

• Primary citation: Landar, A.,Curry, B.,Parker, M.H.,DiGiacomo, R.,Indelicato, S.R.,Nagabhushan, T.L.,Rizzi, G.,Walter, M.R.; Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.; J.Mol.Biol., 299:169-179, 2000; PubMed: 10860730; DOI: 10.1006/jmbi.2000.3734

Experimental method

X-RAY DIFFRACTION (2.9 Å)