1EK5

STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE IN COMPLEX WITH NAD+

Summary for 1EK5

• Entry DOI: 10.2210/pdb1ek5/pdb
• Related: 1EK6
• Descriptor: UDP-GALACTOSE 4-EPIMERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: short-chain dehydrogenase, epimerase, galactosemia, isomerase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38988.03

Authors

Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. (deposition date: 2000-03-06, release date: 2000-05-17, Last modification date: 2024-02-07)

• Primary citation: Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M.; Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.; Biochemistry, 39:5691-5701, 2000; PubMed: 10801319; DOI: 10.1021/bi000215l

Experimental method

X-RAY DIFFRACTION (1.8 Å)