1EJN

UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN INHIBITOR COMPLEX

Summary for 1EJN

Entry DOI	10.2210/pdb1ejn/pdb
Descriptor	UROKINASE-TYPE PLASMINOGEN ACTIVATOR, SULFATE ION, N-(1-ADAMANTYL)-N'-(4-GUANIDINOBENZYL)UREA, ... (4 entities in total)
Functional Keywords	human, upa, plasminogen activator, urokinase, inhibitor complex, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted: P00749
Total number of polymer chains	1
Total formula weight	28881.86
Authors	Sperl, S.,Jacob, U.,Arroyo de Prada, N.,Stuerzebecher, J.,Wilhelm, O.G.,Bode, W.,Magdolen, V.,Huber, R.,Moroder, L. (deposition date: 2000-04-22, release date: 2000-05-17, Last modification date: 2021-11-03)
Primary citation	Sperl, S.,Jacob, U.,Arroyo de Prada, N.,Sturzebecher, J.,Wilhelm, O.G.,Bode, W.,Magdolen, V.,Huber, R.,Moroder, L. (4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase. Proc.Natl.Acad.Sci.USA, 97:5113-5118, 2000 Cited by PubMed: 10805774 DOI: 10.1073/pnas.97.10.5113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation