1EEU

M4L/Y(27D)D/Q89D/T94H mutant of LEN

Summary for 1EEU

Entry DOI	10.2210/pdb1eeu/pdb
Related	1EEQ
Descriptor	KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), ISOPROPYL ALCOHOL (3 entities in total)
Functional Keywords	human kappa-4 immunoglobulin light chain, mutant, aspartic acid in beta-sheet, protein stability, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	25335.97
Authors	Pokkuluri, P.R.,Cai, X.,Gu, M.,Stevens, F.J.,Schiffer, M. (deposition date: 2000-02-03, release date: 2001-02-03, Last modification date: 2023-08-09)
Primary citation	Pokkuluri, P.R.,Gu, M.,Cai, X.,Raffen, R.,Stevens, F.J.,Schiffer, M. Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11:1687-1694, 2002 Cited by PubMed: 12070321 DOI: 10.1110/ps.4920102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation