1EAQ

The RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions modulate DNA binding

Summary for 1EAQ

Entry DOI	10.2210/pdb1eaq/pdb
Related	1CMO 1CO1 1E50 1EAN 1EAO 1H9D 1HJB 1HJC 1IO4
Descriptor	RUNT-RELATED TRANSCRIPTION FACTOR 1, CHLORIDE ION (3 entities in total)
Functional Keywords	transcription/dna, acute myeloid leukemia, aml, runx1, runt domain, chloride binding, transcription factor, ig fold, transcription-dna complex
Biological source	MUS MUSCULUS (MOUSE)
Cellular location	Nucleus : Q03347
Total number of polymer chains	2
Total formula weight	31470.28
Authors	Backstrom, S.,Wolf-Watz, M.,Grundstrom, C.,Hard, T.,Grundstrom, T.,Sauer, U.H. (deposition date: 2001-07-14, release date: 2002-09-12)
Primary citation	Backstrom, S.,Wolf-Watz, M.,Grundstrom, C.,Hard, T.,Grundstrom, T.,Sauer, U.H. The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322:259-, 2002 Cited by PubMed: 12217689 DOI: 10.1016/S0022-2836(02)00702-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation