1E4W
crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment
Summary for 1E4W
| Entry DOI | 10.2210/pdb1e4w/pdb |
| Related | 1E4X 1FBI |
| Descriptor | TAB2, CYCLIC PEPTIDE, NICKEL (II) ION, ... (6 entities in total) |
| Functional Keywords | immune system, complex (antibody-antigen), cross-reactivity, protein-peptide recognition |
| Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
| Total number of polymer chains | 3 |
| Total formula weight | 47482.62 |
| Authors | Hahn, M.,Winkler, D.,Misselwitz, R.,Wessner, H.,Welfle, K.,Zahn, G.,Schneider-Mergener, J.,Hoehne, W. (deposition date: 2000-07-12, release date: 2001-07-12, Last modification date: 2023-12-13) |
| Primary citation | Hahn, M.,Winkler, D.,Welfle, K.,Misselwitz, R.,Welfle, H.,Wessner, H.,Zahn, G.,Scholz, C.,Seifert, M.,Harkins, R.,Schneider-Mergener, J.,Hoehne, W. Cross-Reactive Binding of Cyclic Peptides to an Anti-Tgf Alpha Antibody Fab Fragment: An X-Ray Structural and Thermodynamic Analysis J.Mol.Biol., 314:293-, 2001 Cited by PubMed: 11718562DOI: 10.1006/JMBI.2001.5135 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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