1E33
Crystal structure of an Arylsulfatase A mutant P426L
Summary for 1E33
| Entry DOI | 10.2210/pdb1e33/pdb |
| Related | 1AUK 1E2S 1E3C |
| Descriptor | Arylsulfatase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | hydrolase, cerebroside-3-sulfate hydrolysis, lysosomal enzyme, formylglycine |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 52424.48 |
| Authors | von Buelow, R.,Schmidt, B.,Dierks, T.,von Figura, K.,Uson, I. (deposition date: 2000-06-06, release date: 2001-05-25, Last modification date: 2023-12-06) |
| Primary citation | von Bulow, R.,Schmidt, B.,Dierks, T.,Schwabauer, N.,Schilling, K.,Weber, E.,Uson, I.,von Figura, K. Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy. J. Biol. Chem., 277:9455-9461, 2002 Cited by PubMed: 11777924DOI: 10.1074/jbc.M111993200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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