1E2P

Thymidine kinase, DHBT

Summary for 1E2P

• Entry DOI: 10.2210/pdb1e2p/pdb
• Related: 1E2H 1E2I 1E2J 1E2K 1E2L 1E2M 1E2N 1KI2 1KI4 1KI5 1KI6 1KI7 1KI8 1KIM 1VTK 2VTK 3VTK
• Descriptor: THYMIDINE KINASE, SULFATE ION, 6-[3-HYDROXY-2-(HYDROXYMETHYL)PROPYL]-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE, ... (4 entities in total)
• Functional Keywords: transferase, kinase, dna synthesis, atp-binding
• Biological source: HERPES SIMPLEX VIRUS TYPE 1
• Total number of polymer chains: 2
• Total formula weight: 72178.73

Authors

Schulz, G.E.,Kessler, U. (deposition date: 2000-05-23, release date: 2001-04-26, Last modification date: 2023-12-06)

• Primary citation: Wurth, C.,Kessler, U.,Vogt, J.,Schulz, G.E.,Folkers, G.,Scapozza, L.; The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase; Protein Sci., 10:63-, 2001; PubMed: 11266595; DOI: 10.1110/PS.27401

Experimental method

X-RAY DIFFRACTION (2.5 Å)