1E1Y

Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site

1E1Y の概要

• エントリーDOI: 10.2210/pdb1e1y/pdb
• 関連するPDBエントリー: 1A8I 1ABB 1AXR 1B4D 1BX3 1GPA 1GPB 1GPY 1NOI 1NOJ 1NOK 1PYG 2AMV 2GPA 2GPB 2GPN 2PRI 2PRJ 2SKC 2SKD 2SKE 3AMV 3GPB 4GPB 5GPB 6GPB 7GPB 8GPB 9GPB
• 分子名称: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, PHOSPHITE ION, ... (6 entities in total)
• 機能のキーワード: allosteric inhibition, transferase
• 由来する生物種: ORYCTOLAGUS CUNICULUS (RABBIT)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98199.31

構造登録者

Oikonomakos, N.G.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. (登録日: 2000-05-11, 公開日: 2000-05-17, 最終更新日: 2023-12-06)

• 主引用文献: Oikonomakos, N.G.,Schnier, J.B.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N.; Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site; J.Biol.Chem., 275:34566-, 2000; PubMed: 10924512; DOI: 10.1074/JBC.M004485200

実験手法

X-RAY DIFFRACTION (2.23 Å)