1DZ5

The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein

1DZ5 の概要

• エントリーDOI: 10.2210/pdb1dz5/pdb
• 関連するPDBエントリー: 1AUD 1FHT 1URN
• 分子名称: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3') (2 entities in total)
• 機能のキーワード: ribonucleoprotein-rna complex, polyadenylation, protein protein interaction, rna protein interaction, ribonucleoprotein/rna
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Nucleus: P09012
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 37293.65

構造登録者

Varani, L.,Gunderson, S.I.,Mattaj, I.W.,Kay, L.E.,Neuhaus, D.,Varani, G. (登録日: 2000-02-16, 公開日: 2000-03-29, 最終更新日: 2013-05-15)

• 主引用文献: Varani, L.,Gunderson, S.I.,Mattaj, I.W.,Kay, L.E.,Neuhaus, D.,Varani, G.; The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein; Nat.Struct.Biol., 7:329-, 2000; PubMed: 10742179; DOI: 10.1038/74101

実験手法

SOLUTION NMR