1DYI

ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS

Summary for 1DYI

Entry DOI	10.2210/pdb1dyi/pdb
Descriptor	DIHYDROFOLATE REDUCTASE, CHLORIDE ION, FOLIC ACID, ... (5 entities in total)
Functional Keywords	oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	37034.43
Authors	Reyes, V.M.,Kraut, J. (deposition date: 1994-10-26, release date: 1995-06-03, Last modification date: 2024-02-07)
Primary citation	Reyes, V.M.,Sawaya, M.R.,Brown, K.A.,Kraut, J. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34:2710-2723, 1995 Cited by PubMed: 7873554 DOI: 10.1021/bi00008a039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation