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1DVX

CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DICLOFENAC

Summary for 1DVX
Entry DOI10.2210/pdb1dvx/pdb
Related1BMZ 1DVQ 1DVS 1DVT 1DVU 1DVY 1DVZ
DescriptorTRANSTHYRETIN, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID (3 entities in total)
Functional Keywordsthyroxine transport, signaling protein, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight27138.09
Authors
Klabunde, T.,Petrassi, H.M.,Oza, V.B.,Kelly, J.W.,Sacchettini, J.C. (deposition date: 2000-01-23, release date: 2001-01-23, Last modification date: 2011-07-13)
Primary citationKlabunde, T.,Petrassi, H.M.,Oza, V.B.,Raman, P.,Kelly, J.W.,Sacchettini, J.C.
Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7:312-321, 2000
Cited by
PubMed: 10742177
DOI: 10.1038/74082
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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