1DNC

HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DIGLUTATHIONE-DINITROSO-IRON

Summary for 1DNC

Entry DOI	10.2210/pdb1dnc/pdb
Descriptor	GLUTATHIONE REDUCTASE, PHOSPHATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	sulfhydryl oxidation, sulfinic acid, nitric oxide, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: P00390
Total number of polymer chains	1
Total formula weight	52856.09
Authors	Becker, K.,Savvides, S.N.,Keese, M.,Schirmer, R.H.,Karplus, P.A. (deposition date: 1998-02-20, release date: 1998-05-27, Last modification date: 2011-12-07)
Primary citation	Becker, K.,Savvides, S.N.,Keese, M.,Schirmer, R.H.,Karplus, P.A. Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers. Nat.Struct.Biol., 5:267-271, 1998 Cited by PubMed: 9546215 DOI: 10.1038/nsb0498-267 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation