1DM4

SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7-16)

1DM4 の概要

• エントリーDOI: 10.2210/pdb1dm4/pdb
• 分子名称: PROTEIN (ALPHA THROMBIN:LIGHT CHAIN), PROTEIN (MUTANT ALPHA THROMBIN:HEAVY CHAIN), PROTEIN (FIBRINOPEPTIDE), ... (4 entities in total)
• 機能のキーワード: mutant thrombin, residual catalytic activity, fibrinopeptide a, hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 34907.90

構造登録者

Krishnan, R.,Sadler, E.J.,Tulinsky, A. (登録日: 1999-12-13, 公開日: 2000-01-19, 最終更新日: 2018-03-14)

• 主引用文献: Krishnan, R.,Sadler, J.E.,Tulinsky, A.; Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity.; Acta Crystallogr.,Sect.D, 56:406-410, 2000; PubMed: 10739913; DOI: 10.1107/S0907444900001487

実験手法

X-RAY DIFFRACTION (2.5 Å)