1DG6

CRYSTAL STRUCTURE OF APO2L/TRAIL

Summary for 1DG6

Entry DOI	10.2210/pdb1dg6/pdb
Descriptor	APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL), ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	cytokine, tnf, trimer, zinc-binding site, apoptosis
Biological source	Homo sapiens (human)
Cellular location	Membrane ; Single-pass type II membrane protein : P50591
Total number of polymer chains	1
Total formula weight	22207.69
Authors	Hymowitz, S.G.,O'ConnelL, M.P.,Ultsch, M.H.,de Vos, A.M.,Kelley, R.F. (deposition date: 1999-11-23, release date: 2000-01-26, Last modification date: 2023-08-09)
Primary citation	Hymowitz, S.G.,O'Connell, M.P.,Ultsch, M.H.,Hurst, A.,Totpal, K.,Ashkenazi, A.,de Vos, A.M.,Kelley, R.F. A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL. Biochemistry, 39:633-650, 2000 Cited by PubMed: 10651627 DOI: 10.1021/bi992242l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation