1D6R

CRYSTAL STRUCTURE OF CANCER CHEMOPREVENTIVE BOWMAN-BIRK INHIBITOR IN TERNARY COMPLEX WITH BOVINE TRYPSIN AT 2.3 A RESOLUTION. STRUCTURAL BASIS OF JANUS-FACED SERINE PROTEASE INHIBITOR SPECIFICITY

1D6R の概要

• エントリーDOI: 10.2210/pdb1d6r/pdb
• 分子名称: TRYPSINOGEN, BOWMAN-BIRK PROTEINASE INHIBITOR PRECURSOR (3 entities in total)
• 機能のキーワード: protease inhibitor, serine protease, bowman-birk inhibitor, hydrolase
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29755.83

構造登録者

Koepke, J.,Ermler, U.,Wenzl, G.,Flecker, P. (登録日: 1999-10-15, 公開日: 2000-05-05, 最終更新日: 2017-10-04)

• 主引用文献: Koepke, J.,Ermler, U.,Warkentin, E.,Wenzl, G.,Flecker, P.; Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.; J.Mol.Biol., 298:477-491, 2000; PubMed: 10772864; DOI: 10.1006/jmbi.2000.3677

実験手法

X-RAY DIFFRACTION (2.3 Å)