1D6R

CRYSTAL STRUCTURE OF CANCER CHEMOPREVENTIVE BOWMAN-BIRK INHIBITOR IN TERNARY COMPLEX WITH BOVINE TRYPSIN AT 2.3 A RESOLUTION. STRUCTURAL BASIS OF JANUS-FACED SERINE PROTEASE INHIBITOR SPECIFICITY

Summary for 1D6R

Entry DOI	10.2210/pdb1d6r/pdb
Descriptor	TRYPSINOGEN, BOWMAN-BIRK PROTEINASE INHIBITOR PRECURSOR (3 entities in total)
Functional Keywords	protease inhibitor, serine protease, bowman-birk inhibitor, hydrolase
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	2
Total formula weight	29755.83
Authors	Koepke, J.,Ermler, U.,Wenzl, G.,Flecker, P. (deposition date: 1999-10-15, release date: 2000-05-05, Last modification date: 2017-10-04)
Primary citation	Koepke, J.,Ermler, U.,Warkentin, E.,Wenzl, G.,Flecker, P. Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity. J.Mol.Biol., 298:477-491, 2000 Cited by PubMed: 10772864 DOI: 10.1006/jmbi.2000.3677 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation