1D3V

CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG

Summary for 1D3V

Entry DOI	10.2210/pdb1d3v/pdb
Descriptor	PROTEIN (ARGINASE), MANGANESE (II) ION, 2(S)-AMINO-6-BORONOHEXANOIC ACID, ... (4 entities in total)
Functional Keywords	binuclear manganese cluster, boronic acid inhibitor, perfectly twinned crystal, hydrolase
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Cytoplasm: P07824
Total number of polymer chains	2
Total formula weight	70641.94
Authors	Cox, J.D.,Kim, N.N.,Traish, A.M.,Christianson, D.W. (deposition date: 1999-10-01, release date: 1999-11-17, Last modification date: 2024-02-07)
Primary citation	Cox, J.D.,Kim, N.N.,Traish, A.M.,Christianson, D.W. Arginase-boronic acid complex highlights a physiological role in erectile function. Nat.Struct.Biol., 6:1043-1048, 1999 Cited by PubMed: 10542097 DOI: 10.1038/14929 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation